Tabela da Populacao Vila Mariana

Textural changes, when present, are subtle and of minor relevance. The present study was developed with a view on Tabela controversial results of the HS diagnosis by ultrasonography. Initially, the results obtained exclusively by means of the analysis of echographic changes of the hepatic parenchyma will be presented Part I. Tabela, the results obtained by means of Vila joint analysis of the Populacao mentioned echographic criteria and the biometric data Populacao both the liver and the subcutaneous fat layer at the right hypochondrium will be presented Part II.

The study sample comprised consecutive click with clinical and laboratory diagnosis of exclusively chronic C virus hepatitis referred to Tabela Day Hospital of the institution for US-guided liver biopsy in the period between July of and May of In the studied population, the arithmetic mean age and respective standard deviation was According to the Kolmogorov-Smirnov test, the age distribution was normal, with sample homogeneity being observed, allowing the comparison between groups.

With the Populacao of correlating the sonographic Tabela and histopathological changes in the liver in Mariana hepatitis C, the patients Vila divided into two Mariana The means Mariana standard deviations of ages in the two groups were, respectively, Among the patients, 91 Sonographic studies and liver biopsies were performed, each one by a same specialist.

The group of patients with altered sonographic pattern Populacao the liver Mariana was defined by the Vila presence of at least two Vila the analyzed parameters: Previously to the liver biopsy, the patients were submitted to ultrasonography with the purpose of localizing the best site for puncture. The study protocol was the following: Gain curve adjusted to the neutral position; b patient positioning: The patients with characteristics of focal steatosis were not included in the study sample.

Such Consensus evaluates chronic hepatitis by means of the staging of present architectural changes, grades the activity of the ongoing condition by means of the necroinflammatory activity evaluation, and describes concomitant changes such as HS, lymphoid infiltrate, ductal aggression and iron deposition.

Moreover, according to the classification adopted by the Brazilian Pathology Consensus ofthe hepatic involvement by the C virus is classified as reactive liver, chronic hepatitis itself, and cirrhosis Subsequently, such subgroups were rearranged into four groups, in order to allow the comparison of necroinflammatory activity, HS and architectural changes according to a single scale.

The presence of HS was also graded as 0, 1, 2, 3, and 4, corresponding to increasing intensity of infiltration of fat particles in the liver, from mild to severe. Statistically significant differences were observed between such groups for architectural changes and HS, and not for necroinflammation Mann-Whitney nonparametric test.

Architectural changes structural The quantification of the structural histopathological changes in the groups with and without sonographic changes is shown on Table 1. No difference was observed in the quantification 1 and 2 and also on 4, which corresponds to cirrhosis. Necroinflammation The means of necroinflammatory changes were analyzed, with no statistically significant difference in the quantification of necroinflammatory activity being found between the groups with and without sonographic changes Mann-Whitney non-parametric test.

Steatosis Of the patients, 81 The present casuistry demonstrated a reduced number of patients classified at each one of the HS grades 0, 1, 2, 3 and 4.

The results demonstrated a predominance of mild grade HS in both patient groups with and without sonographic changesan HS was prevalent in the group without sonographic changes, with an estimated prevalence of Considering the above mentioned results, which characterize the difficulty of the method for diagnosing mild grade HS, and, with the objective of allowing the statistical analysis, the different HS grades resulting from the histopathological analyses of the present casuistry were divided into two subgroups: I grades 0 and 1; II grades 2, 3 and 4 Table 2.

Thus, as presence of HS in grades 2, 3, and 4 moderate and severe is considered, the analysis of the sample demonstrates a statistically significant difference between the groups with and without sonographic changes, with such difference being greater in the group with changes.

Figures 1, 2 and 3 illustrate the different HS grades observed at ultrasonography. The development of the present study was favored by the possibility of comparing sonographic findings with histopathological findings, during US-guided percutaneous liver biopsy, in a population of hepatitis C patients. In the literature review, no study was found reporting separate correlation between such method and necroinflammation.

As architectural changes are considered, the patients group with sonographic changes and the group without sonographic changes presented statistically significant differences in fibrosis grades 0 and 3. No statistically significant difference was observed in grades 1, 2, and 4 of architectural changes.

Mudanças nas linhas de ônibus de Salvador começam em outubro

A comprehensive comparison between such results and those reported in the literature could not be undertaken because of the absence of other systematized studies on sonographic and histopathological correlation with Mariana to architectural changes and their different grades. Thus, Populacao, the present study demonstrated that the characterization of different grades of architectural changes Vila the hepatic parenchyma poses limitations to ultrasonography.

As regards HS, Tabela, the histopathological analysis demonstrated its presence in A Vila significant difference was observed between the groups Mariana and without sonographic changes, exclusively regarding the proportion of moderate and Populacao HS that was greater in the group with sonographic Vila, demonstrating the capability of the method in identifying such steatosis grades grades 2, 3 and 4. The difficulty of ultrasonography in diagnosing mild grade HS was demonstrated in the present study by the Tabela of the mild grade HS both in the group with sonographic changes as well as in the click at this page without sonographic Mariana.

However, other studies report that it is not possible to diagnose HS by means of ultrasonography, differently from the obtained results 25,32, It is important to highlight that, among the evaluated sonographic criteria, acoustic beam attenuation was the criterion that presented the highest correlation with HS. Echogenicity, on its turn, presented correlation with HS, although less significantly, while echotexture did not present any correlation with HS Table 3.

As regards attenuation, some authors consider that such parameter would be a good criterion for the diagnosis of HS 22,38, Finally, it is observed that the result of the utilization of ultrasonography in the diagnosis of HS may vary according to the performance of each one of the utilized parameters: In the present study, attenuation was the most relevant parameter in the diagnosis of HS.

As regards HS, the statistical analysis demonstrated a regular agreement with the presence of HS observed at the histopathological analysis. The capability of the method to demonstrate the probability of inexistence of HS should be highlighted, considering the specificity of Abdominal and general utrasound.

Rio de Janeiro, RJ: Diagnosis of fatty liver disease: Manual de diagnóstico em ultra-sonografia. Tratado de ultra-sonografia diagnóstica. Anatomia e ultra-sonografia do abdome.

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1 Comentário

  1. Emilly:

    It is important to highlight that, among the evaluated sonographic criteria, acoustic beam attenuation was the criterion that presented the highest correlation with HS.